Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16211318 | 0.89 | CA1 (0.56) | MRGPRX4NPC1RAB9ACA1CA2 | |
| SCHEMBL15761745 | 0.87 | HIF1A (0.65) | HIF1ASENP1LOXL2NPC1RAB9A | |
| SCHEMBL15761756 | 0.84 | HIF1A (0.61) | MRGPRX4HIF1ASENP1LOXL2EGFR | |
| SCHEMBL5179550 | 0.84 | HIF1A (0.68) | MRGPRX4HIF1ASENP1FFAR1CA1 | |
| SCHEMBL20237137 | 0.82 | RAB9A (0.49) | MRGPRX4HIF1ANPC1RAB9AEGFR | |
| SCHEMBL15761730 | 0.82 | HIF1A (0.65) | MRGPRX4HIF1ASENP1LOXL2NPC1 | |
| SCHEMBL15761753 | 0.82 | HIF1A (0.85) | MRGPRX4HIF1ASENP1LOXL2RAB9A | |
| SCHEMBL7055657 | 0.81 | MRGPRX4 (0.63) | MRGPRX4LOXL2NPC1RAB9ACYP4F2 | |
| SCHEMBL15761744 | 0.81 | HIF1A (0.67) | HIF1ASENP1LOXL2EGFRCYP4F2 | |
| SCHEMBL15755382 | 0.81 | HIF1A (0.70) | MRGPRX4HIF1ASENP1LOXL2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137518-A | As 6 inhibitor of histone deacetylase 1,3,4- oxadiazole derivatives compound and include its pharmaceutical composition | 株式会社钟根堂 | 2018-06-08 | — | — | CN | disclosed |