Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.63 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.53 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27425788 | 0.92 | MRGPRX4 (0.56) | MRGPRX4TAS1R3TAS1R1TAS1R2TP53 | |
| SCHEMBL7468439 | 0.91 | MRGPRX4 (0.55) | MRGPRX4TAS1R3TAS1R1TAS1R2TP53 | |
| SCHEMBL5328114 | 0.87 | MRGPRX4 (0.51) | MRGPRX4TAS1R3TAS1R1TAS1R2TP53 | |
| SCHEMBL4035515 | 0.87 | MAPT (0.56) | MRGPRX4TP53SMN1; SMN2GPR139NPC1 | |
| SCHEMBL23518951 | 0.87 | NOTUM (0.59) | MRGPRX4TAS1R3TAS1R1TAS1R2TP53 | |
| SCHEMBL23343631 | 0.86 | SMN1; SMN2 (0.54) | MRGPRX4TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7842792 | 0.85 | SMN1; SMN2 (0.52) | MRGPRX4TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29742938 | 0.84 | MAOB (0.55) | TAS1R3TAS1R1TAS1R2TP53KAT6A | |
| SCHEMBL697586 | 0.84 | MAOB (0.55) | TAS1R3TAS1R1TAS1R2TP53KAT6A | |
| SCHEMBL30184372 | 0.84 | TAS1R3 (0.56) | MRGPRX4TAS1R3TAS1R1TAS1R2KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076607-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-05-24 | — | — | CN | disclosed |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YROK (US) | 2023-09-19 | — | — | US | disclosed |
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |
| WO-2023097386-A1 | SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS | EUROFARMA LABORATÓRIOS S.A (BR) | 2023-06-08 | — | — | WO | disclosed |
| CN-116018344-A | Pesticidally active heterocyclic derivatives with sulfur containing substituents | 先正达农作物保护股份公司 | 2023-04-25 | — | — | CN | disclosed |
| US-20220372033-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2022-11-24 | — | — | US | disclosed |
| CN-115023426-A | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达农作物保护股份公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-113811532-A | Pesticidally active heterocyclic derivatives with sulfur-containing substituents | 先正达农作物保护股份公司 | 2021-12-17 | — | — | CN | disclosed |
| WO-2021063915-A1 | ANTIBACTERIAL COMPOUNDS | Janssen Sciences Ireland Unlimited Company (IE) | 2021-04-08 | — | — | WO | disclosed |
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2021-02-04 | — | — | US | disclosed |
| CN-107793413-A | Pyrimidine heterocyclic compound and its preparation method and application | 天津滨江药物研发有限公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-105061350-A | Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | RECEPTOS INC | 2015-11-18 | — | — | CN | disclosed |
| CN-102762100-B | Selective sphingosine-1-phosphate receptor modulators and chiral synthesis methods | RECEPTOS INC | 2015-07-01 | — | — | CN | disclosed |
| US-20030119816-A1 | Flavone derivatives, preparation method and use as medicines | AVENTIS PHARMA S.A. (FR) | 2003-06-26 | — | — | US | disclosed |
| EP-0634404-A1 | Phtalazin derivatives and their use as pesticides | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220372033-A1 | ANTIBACTERIAL COMPOUNDS | NDUFS3, SQOR, MT-ND4 | MRGPRX4 2637/4885TAS1R3 3444/4885TAS1R1 3073/4885 |
| US-20030119816-A1 | Flavone derivatives, preparation method and use as medicines | REN, CYP2F1, CYP3A43 | MRGPRX4 803/4885TAS1R3 2676/4885TAS1R1 2283/4885 |
| US-20210032181-A1 | DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME | AFF2, AFF4, AFF1 | MRGPRX4 3438/4885TAS1R3 4295/4885TAS1R1 4348/4885 |
| US-11760701-B2 | Difluoromethoxylation and trifluoromethoxylation compositions and methods for synthesizing same | AFF2, AFF4, AFF1 | MRGPRX4 3438/4885TAS1R3 4295/4885TAS1R1 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.