Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 7/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27701881 | 0.93 | TBXAS1 (0.45) | TBXAS1TAAR1FDPSGAASMN1; SMN2 | |
| Acrylic Acid SCHEMBL28317803 | 0.93 | TBXAS1 (0.45) | TBXAS1TAAR1FDPSGAASMN1; SMN2 | |
| Urea SCHEMBL28287104 | 0.91 | TBXAS1 (0.42) | TBXAS1TAAR1FDPSGAASMN1; SMN2 | |
| Benzene SCHEMBL2482857 | 0.90 | TAAR1 (0.50) | TBXAS1TAAR1SMN1; SMN2ALOX15HTR1A | |
| SCHEMBL11317 | 0.90 | — | — | |
| Glycine SCHEMBL28230588 | 0.90 | TBXAS1 (0.46) | TBXAS1TAAR1FDPSGAASMN1; SMN2 | |
| Bromide SCHEMBL29170666 | 0.88 | ALOX15 (0.44) | TBXAS1TAAR1FDPSSMN1; SMN2ALOX15 | |
| Water SCHEMBL28393920 | 0.88 | ALOX15 (0.44) | TBXAS1TAAR1FDPSSMN1; SMN2ALOX15 | |
| SCHEMBL10484488 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL3806550 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101996-B | Method for producing cellulosic proton type ionic liquid by using cellulose | 贵州大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-108101996-A | Utilize the method for cellulose production cellulose material subtype ionic liquid | 贵州大学 | 2018-06-01 | — | — | CN | disclosed |