Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | PTPRF | P10586 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | CDC25B | P30305 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219791 | 0.87 | HTR2C (0.35) | — | |
| SCHEMBL28302273 | 0.85 | — | — | |
| SCHEMBL28219444 | 0.85 | EDNRB (0.36) | ALDH1A1MAPK1 | |
| SCHEMBL28860142 | 0.84 | TAAR1 (0.39) | — | |
| SCHEMBL28219808 | 0.82 | HSD11B1 (0.32) | — | |
| SCHEMBL28302319 | 0.82 | ESR2 (0.34) | — | |
| SCHEMBL28219413 | 0.82 | CYP2A6 (0.36) | PTPRC | |
| SCHEMBL28219790 | 0.82 | IMPDH2 (0.33) | — | |
| SCHEMBL28860141 | 0.81 | IDO1 (0.36) | ALDH1A1MAPK1 | |
| SCHEMBL28219407 | 0.80 | TNKS2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109824802-A | Metallocenic compound, catalyst system and the polymerization using them of bridging | 埃克森美孚化学专利公司 | 2019-05-31 | — | — | CN | claimed |
| CN-109824802-A | Metallocenic compound, catalyst system and the polymerization using them of bridging | 埃克森美孚化学专利公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-108137729-A | It is used to form the catalyst of multimodal polymer | 埃克森美孚化学专利公司 | 2018-06-08 | — | — | CN | disclosed |