Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL28219947

CCS(N)(=O)=O.O=C(O)C(F)(F)F

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA12 O43570 2/20 0.37
CA9 Q16790 2/20 0.37
CA7 P43166 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
FAAH O00519 11/20 0.35
CES1 P23141 6/20 0.35
CES2 O00748 4/20 0.35
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5310917 0.86 FAAH (0.39) ALDH1A1L3MBTL1CA1CA2CA12
Trifluoroacetic Acid SCHEMBL34466006 0.84 ALDH1A1 (0.40) ALDH1A1L3MBTL1CA1CA2CA12
Trifluoroacetic Acid SCHEMBL3845260 0.83 CA1 (0.47) ALDH1A1L3MBTL1CA1CA2CA12
Trifluoroacetic Acid SCHEMBL30657138 0.83 CA1 (0.47) ALDH1A1L3MBTL1CA1CA2CA12
Trifluoroacetic Acid SCHEMBL30605511 0.83 ALDH1A1 (0.48) ALDH1A1L3MBTL1CA1CA2CA12
Trifluoroacetic Acid SCHEMBL18246400 0.83 FAAH (0.44) CA2FAAHCES1CES2MEN1
Trifluoroacetic Acid SCHEMBL27903040 0.81 ALDH1A1 (0.48) ALDH1A1L3MBTL1FAAHCES1CES2
Trifluoroacetic Acid SCHEMBL17258930 0.81 FAAH (0.51) CA2FAAHCES1CES2MEN1
Trifluoroacetic Acid SCHEMBL359979 0.80 FAAH (0.39) ALDH1A1FAAHCES1CES2MEN1
Trifluoroacetic Acid SCHEMBL6224514 0.80 FAAH (0.39) ALDH1A1FAAHCES1CES2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025081019-A1 KIF MODULATOR COMPOUNDS AND METHODS OF USE IAMBIC THERAPEUTICS, INC. (US) 2025-04-17 WO disclosed
CN-117964541-A Pyrrole sulfonyl derivative, and preparation method and application thereof 天地恒一制药股份有限公司 2024-05-03 CN disclosed
CN-108137545-A TRIAZOLE AGONISTS OF THE APJ RECEPTOR 美国安进公司 2018-06-08 CN disclosed