Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819562 | 0.96 | USP2 (0.37) | KMT2ATDP1USP2GRM1ALDH1A1 | |
| SCHEMBL23653190 | 0.87 | USP2 (0.37) | KMT2AHTTUSP2GRM1ALDH1A1 | |
| SCHEMBL2823475 | 0.85 | USP2 (0.36) | KMT2ASMN1; SMN2TDP1USP2L3MBTL1 | |
| SCHEMBL2823051 | 0.83 | MMP13 (0.34) | KMT2ASMN1; SMN2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL2823045 | 0.82 | KMT2A (0.33) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2821636 | 0.82 | GAA (0.36) | KMT2AHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL2851123 | 0.81 | KDM4E (0.34) | KMT2AHTTSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2822078 | 0.81 | MMP13 (0.37) | KMT2ATDP1L3MBTL1ALDH1A1MMP13 | |
| SCHEMBL5833104 | 0.80 | GPR119 (0.31) | — | |
| SCHEMBL2823000 | 0.80 | USP2 (0.37) | KMT2AHTTSMN1; SMN2TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1386914-B1 | HALOGENATED QUINOLINE DERIVATIVES AND ECTOPARASITE CONTROLLERS | MEIJI SEIKA KAISHA (JP) | 2010-10-27 | — | — | EP | disclosed |