Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757122 | 0.74 | KDM5A (0.43) | KCNH2ALDH1A1GPR52 | |
| SCHEMBL27539141 | 0.74 | KDM4C (0.52) | — | |
| SCHEMBL17737834 | 0.70 | KMT2A (0.46) | NR1H2NR1H3ALDH1A1GAAHSD17B10 | |
| SCHEMBL27160505 | 0.70 | RECQL (0.44) | DRD2NR1H2NR1H3CYP4F2CYP4A11 | |
| SCHEMBL30046411 | 0.70 | HTT (0.56) | KCNH2DRD2GAAHSD17B10 | |
| SCHEMBL1887800 | 0.69 | TAAR1 (0.46) | DRD2NR1H2NR1H3ALDH1A1GAA | |
| SCHEMBL8233359 | 0.69 | ALDH1A1 (0.47) | DRD2ALDH1A1GAAHSD17B10SIGMAR1 | |
| SCHEMBL7054313 | 0.69 | ALDH1A1 (0.47) | DRD2CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL2378354 | 0.68 | ALDH1A1 (0.44) | DRD2CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL8278304 | 0.68 | ALDH1A1 (0.51) | DRD2ALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137600-A | Condensed pyrazole derivatives as kinase inhibitor | UCB生物制药私人有限公司 | 2018-06-08 | — | — | CN | disclosed |