Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28017031 | 0.85 | ALOX15 (0.46) | ALOX15KMT2AHRH4L3MBTL1HSP90AA1 | |
| Diaminopyrimidine SCHEMBL4408151 | 0.82 | L3MBTL1 (0.40) | HRH4HRH3CXCR4L3MBTL1HSP90AA1 | |
| Diaminopyrimidine SCHEMBL1290828 | 0.82 | L3MBTL1 (0.40) | HRH4HRH3CXCR4L3MBTL1HSP90AA1 | |
| SCHEMBL29531700 | 0.81 | — | — | |
| SCHEMBL91470 | 0.81 | — | — | |
| Fumaric Acid SCHEMBL30838061 | 0.81 | ALOX15 (0.42) | ALOX15KMT2AL3MBTL1HSP90AA1AURKA | |
| Maleic Acid SCHEMBL27590355 | 0.81 | ALOX15 (0.42) | ALOX15KMT2AL3MBTL1HSP90AA1AURKA | |
| Hydrochloric Acid SCHEMBL7006388 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL30978373 | 0.79 | — | — | |
| Trifluoroacetic Acid SCHEMBL2723371 | 0.78 | HSP90AB1 (0.55) | HSP90AA1HSP90AB1SMN1; SMN2NUDT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108135175-A | Bicyclic compounds and their use for inhibition of SUV39H2 | 肿瘤疗法科学股份有限公司 | 2018-06-08 | — | — | CN | disclosed |