Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.38 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650207 | 0.87 | CRBN (0.52) | CRBNDDB1ALDH1A1LMNA | |
| Water SCHEMBL28246784 | 0.87 | CRBN (0.52) | CRBNDDB1ALDH1A1LMNA | |
| Triphosphate SCHEMBL869856 | 0.86 | ENPP1 (0.51) | ENPP1P2RY2P2RY6P2RY4 | |
| Benzene SCHEMBL26606841 | 0.85 | CRBN (0.55) | CRBNDDB1 | |
| Furan SCHEMBL1628664 | 0.77 | CRBN (0.43) | CRBNDDB1 | |
| SCHEMBL27804578 | 0.76 | CRBN (0.41) | CRBNDDB1 | |
| Pyridine SCHEMBL27912026 | 0.76 | CRBN (0.46) | CRBNDDB1ALDH1A1 | |
| Pyrimidine SCHEMBL2836405 | 0.76 | CRBN (0.42) | CRBNDDB1 | |
| Ribose (Furanose) SCHEMBL2406693 | 0.71 | SLC28A1 (0.63) | P2RY2P2RY6P2RY14P2RY4 | |
| SCHEMBL1433847 | 0.69 | ENPP1 (0.46) | CRBNDDB1ENPP1P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108272854-A | A kind of drug and preparation method thereof for preventing chemotherapy induced stomatitis disease | 青岛金丽雅医疗新技术发展有限公司 | 2018-07-13 | — | — | CN | disclosed |