SCHEMBL28220192

SCHEMBL28220192

NC(=O)CC1(CC(N)=O)CCCCC1

nearest known ligand 0.83

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 1/20 0.52
TSHR P16473 1/20 0.52
BLM P54132 1/20 0.52
CACNA2D1 P54289 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CYP2C19 P33261 1/20 0.39
HSD11B1 P28845 3/20 0.39
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11340444 0.97 CYP1A2 (0.48) ALDH1A1USP2LMNACYP1A2TSHR
Hydrochloric Acid SCHEMBL4826505 0.95 CYP1A2 (0.46) ALDH1A1USP2LMNACYP1A2TSHR
SCHEMBL2454102 0.91 ALDH1A1 (0.67) ALDH1A1USP2LMNACYP1A2TSHR
Ammonia Solution, Strong SCHEMBL28636892 0.89 ALDH1A1 (0.64) ALDH1A1USP2LMNACYP1A2TSHR
SCHEMBL13544534 0.88 ALDH1A1 (0.63) ALDH1A1USP2LMNACYP1A2TSHR
SCHEMBL10064999 0.88 ALDH1A1 (0.69) ALDH1A1USP2LMNACYP1A2TSHR
SCHEMBL4875150 0.87 USP2 (0.42) ALDH1A1USP2LMNACYP1A2TSHR
Hydrochloric Acid SCHEMBL4826508 0.86 ALDH1A1 (0.61) ALDH1A1USP2LMNACYP1A2TSHR
SCHEMBL13544799 0.86 ALDH1A1 (0.41) ALDH1A1USP2LMNACYP1A2TSHR
SCHEMBL14494687 0.86 LMNA (0.45) ALDH1A1USP2LMNACYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611945-B Water-soluble phosphoric acid derivative, preparation method thereof, pharmaceutical composition and application 北京森妙生物科技有限公司 2025-03-11 CN disclosed
CN-119462640-A Pyridine [3,2-d ] pyrimidine-2-amine derivative, and preparation method and application thereof 北京森妙生物科技有限公司 2025-02-18 CN disclosed
CN-114685491-B Pyridin-2-amine derivatives, pharmaceutical compositions and uses thereof 清华大学 2024-01-12 CN disclosed
CN-109232508-B Preparation method of 1, 1-cyclohexyl diacetic anhydride 河北三川化工有限公司 2022-05-27 CN disclosed
CN-114025844-A Protein tyrosine phosphatase inhibitors and methods of use thereof 卡里科生命科学有限责任公司 2022-02-08 CN disclosed
CN-108779111-B Deoxycytidine kinase binding compounds 加利福尼亚大学董事会 2021-11-12 CN disclosed
CN-108069963-A Pyridopyrimidine derivatives or its salt and its preparation method, pharmaceutical composition and purposes 清华大学 2018-05-25 CN disclosed