Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | MET | P08581 | 3/20 | 0.56 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605504 | 1.00 | L3MBTL1 (0.65) | L3MBTL1METALDH3A1POLBHTT | |
| SCHEMBL29605685 | 0.90 | L3MBTL1 (0.60) | L3MBTL1METALDH3A1POLBHTT | |
| SCHEMBL29605804 | 0.85 | L3MBTL1 (0.51) | L3MBTL1METALDH3A1POLBHTT | |
| SCHEMBL21295073 | 0.84 | MET (0.65) | L3MBTL1METHTTPKMCYP2C19 | |
| SCHEMBL29847193 | 0.84 | MET (0.65) | L3MBTL1METHTTPKMCYP2C19 | |
| SCHEMBL26969513 | 0.81 | L3MBTL1 (0.57) | L3MBTL1METALDH3A1POLBHTT | |
| SCHEMBL27873471 | 0.80 | L3MBTL1 (0.52) | L3MBTL1METALDH3A1POLBHTT | |
| SCHEMBL1749202 | 0.79 | L3MBTL1 (0.62) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL3616325 | 0.79 | MET (0.76) | L3MBTL1METALDH3A1POLBHTT | |
| SCHEMBL4532804 | 0.79 | L3MBTL1 (1.00) | L3MBTL1METALDH3A1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110117285-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-108218873-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2018-06-29 | — | — | CN | disclosed |