SCHEMBL28223371

SCHEMBL28223371

CCCC/C=C/CS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 1/20 0.58
ALDH1A1 P00352 6/20 0.50
CYP2C9 P11712 2/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
MCHR1 Q99705 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.42
G6PD P11413 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
TLR9 Q9NR96 1/20 0.40
LMNA P02545 1/20 0.40
ALB P02768 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
GAA P10253 1/20 0.39
GFER P55789 1/20 0.39
HSD17B10 Q99714 1/20 0.38
PDE5A O76074 1/20 0.38
CA12 O43570 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11038225 0.86 CTSK (0.75) CTSKALDH1A1CYP2C9CYP3A4CYP2C19
SCHEMBL11400294 0.82 CTSK (0.66) CTSKALDH1A1CYP2C9CYP3A4CYP2C19
SCHEMBL9421623 0.79 EPHX2 (0.53) ALDH1A1CYP2C9CYP3A4CYP2C19LMNA
SCHEMBL9136600 0.79 EPHX2 (0.53) ALDH1A1CYP2C9CYP3A4CYP2C19LMNA
SCHEMBL9421619 0.79 EPHX2 (0.53) ALDH1A1CYP2C9CYP3A4CYP2C19LMNA
SCHEMBL9136605 0.79 EPHX2 (0.53) ALDH1A1CYP2C9CYP3A4CYP2C19LMNA
SCHEMBL28173791 0.77 CTSK (0.64) CTSKALDH1A1CYP2C9CYP3A4CYP2C19
SCHEMBL11250504 0.77 CTSK (0.68) CTSKALDH1A1CYP2C9CYP3A4CYP2C19
SCHEMBL3013104 0.74 ALDH1A1 (0.80) CTSKALDH1A1CYP2C9CYP3A4CYP2C19
SCHEMBL7426233 0.74 CTSK (0.44) CTSKALDH1A1CYP2C9CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108191625-B (E) Preparation method of (E) -1- (4-hydroxy-3-methoxyphenyl) -4-en-3-decanone 厦门云凡医药科技有限公司 2021-08-03 CN disclosed
CN-108191625-A (E) preparation method of ten ketone of -1- (4- hydroxy 3-methoxybenzenes base) -4- alkene -3- 厦门云凡医药科技有限公司 2018-06-22 CN disclosed