Algestone Acetophenide

Algestone Acetophenide

SCHEMBL282250

CC(=O)[C@@]12O[C@](C)(c3ccccc3)O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]12C

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 2/20 0.76
SERPINA6 P08185 4/20 0.56
SHBG P04278 6/20 0.55
LMNA P02545 5/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
NR3C1 P04150 4/20 0.55
CYP2C19 P33261 4/20 0.55
MAPT P10636 3/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
ADORA3 P0DMS8 2/20 0.55
BLM P54132 2/20 0.55
MAPK3 P27361 1/20 0.55
SLC6A3 Q01959 1/20 0.55
ALDH1A1 P00352 3/20 0.51
PGR P06401 3/20 0.51
ADRA1A P35348 2/20 0.51
HTR2B P41595 2/20 0.51
CYP3A4 P08684 4/20 0.48
TSHR P16473 4/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Algestone Acetophenide SCHEMBL3039564 1.00 CYP17A1 (0.76) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
Algestone Acetophenide SCHEMBL1649218 1.00 CYP17A1 (0.76) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
Algestone Acetonide SCHEMBL42582 0.87 CYP17A1 (0.85) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
SCHEMBL7993136 0.87 CYP17A1 (1.00) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
SCHEMBL29500568 0.87 CYP17A1 (1.00) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
SCHEMBL4541005 0.87 CYP17A1 (1.00) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
SCHEMBL29409283 0.87 CYP17A1 (1.00) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
SCHEMBL4539514 0.87 CYP17A1 (1.00) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
SCHEMBL151266 0.77 CYP17A1 (0.76) CYP17A1SERPINA6SHBGLMNASMN1; SMN2
SCHEMBL19505758 0.76 SHBG (0.53) CYP17A1SERPINA6SHBGLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 629 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3501543-A1 METHOD FOR MANUFACTURING VAGINAL DRUG DELIVERY SYSTEMS USING A THREE DIMENSIONAL PRINTER Delim Cosmetics & Pharma S.r.l. (IT) 2019-06-26 EP claimed
CN-106866777-B The preparation method of algestone acetophenide 杭州弘任医药科技有限公司 2019-05-24 CN claimed
CN-106866777-A The preparation method of algestone acetophenide 杭州弘任医药科技有限公司 2017-06-20 CN claimed
US-20160008376-A1 Compositions, Methods and Uses for Treating Gender-Biased Immune Disorders BIOCOPEA LIMITED (GB) 2016-01-14 US claimed
WO-2016005599-A1 COMPOSITIONS, METHODS AND USES FOR TREATING GENDER-BIASED IMMUNE DISORDERS BIOCOPEA LIMITED (GB) 2016-01-14 WO claimed
US-20120189599-A1 MEDICATION FOR ORAL ADMINISTRATION, COMPRISING AT LEAST ONE ESTROGEN AND/OR AT LEAST ONE GESTAGEN AND AT LEAST ONE PROBIOTIC BACTERIAL STRAIN BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2012-07-26 US claimed
EP-2116249-B1 Pharmaceutical compound containing gestagens and/or oestrogens and 5-methyl-(6S)-tetrahydrofolates Bayer Pharma AG (DE) 2012-05-02 EP claimed
EP-1888077-B1 PHARMACEUTICAL COMPOSITION CONTAINING GESTAGENS AND/OR ESTROGENS AND 5-METHYL-(6S)-TETRAHYDROFOLATE BAYER SCHERING PHARMA AG (DE) 2009-04-29 EP claimed
US-20080280861-A1 Method of Female Contraception and a Kit For Use Therein PANTARHEI BIOSCIENCE B.V. (NL) 2008-11-13 US claimed
US-20080234240-A1 Extended Use Combination Comprising Estrogens And Progestins SCHERING AG (DE) 2008-09-25 US claimed
EP-0786999-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1999-01-20 EP claimed
EP-0792371-A4 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO INC (US) 1998-12-30 EP claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
EP-0136011-B1 A method of hormonal treatment of peri-menopausal, menopausal and post-menopausal disorders and multi-preparation pack therefor PRE JAY HOLDINGS LTD (CA) 1997-01-22 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
US-4826831-A Method of hormonal treatment for menopausal or post-menopausal disorders involving continuous administration of progestogens and estrogens PRE JAY HOLDINGS LIMITED (CA) 1989-05-02 US claimed
US-4346709-A Drug delivery devices comprising erodible polymer and erosion rate modifier ALZA CORPORATION (US) 1982-08-31 US claimed