SCHEMBL28225233

SCHEMBL28225233

CCCOC(=O)CC(CCC(C)C)CCC(C)C

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.37
CYP19A1 P11511 1/20 0.36
NAAA Q02083 1/20 0.34
DGKA P23743 1/20 0.34
ALDH1A1 P00352 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
TLR4 O00206 1/20 0.34
RECQL P46063 1/20 0.33
ACHE P22303 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11090796 0.88 CYP19A1 (0.45) CYP19A1ALDH1A1TDP1ACHEL3MBTL1
SCHEMBL4888992 0.82 CACNA2D1 (0.38) HCAR2NAAADGKAALDH1A1L3MBTL1
SCHEMBL25544316 0.82 NAAA (0.55) HCAR2NAAADGKAL3MBTL1MAPT
SCHEMBL133737 0.81 MMP1 (0.42) HCAR2NAAADGKAALDH1A1TDP1
SCHEMBL5973579 0.80 MGAM (0.44) ALDH1A1TDP1L3MBTL1CYP3A4TSHR
SCHEMBL5076562 0.79 TLR4 (0.51) NAAADGKATDP1TLR4RECQL
SCHEMBL5075448 0.79 TLR4 (0.51) NAAADGKATDP1TLR4RECQL
SCHEMBL5075384 0.79 TLR4 (0.51) NAAADGKATDP1TLR4RECQL
SCHEMBL5074137 0.79 TLR4 (0.51) NAAADGKATDP1TLR4RECQL
SCHEMBL28183616 0.79 TSHR (0.42) CYP19A1NAAADGKAALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250369-A A kind of preparation method of low smell high-weatherability polymer polyatomic alcohol 万华化学集团股份有限公司 2018-07-06 CN disclosed