Piperidine

Piperidine

SCHEMBL2822529

C1CCNCC1.C=CC=C

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.64
CXCR4 P61073 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.33
MAPT P10636 1/20 0.33
PDE4A P27815 1/20 0.33
KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrrolidine SCHEMBL21327985 0.93 ALDH1A1 (0.53) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Butadiene SCHEMBL15251839 0.84
Piperidine SCHEMBL28278815 0.83
Piperidine SCHEMBL5441409 0.81
SCHEMBL8253733 0.80 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL21753221 0.80 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL3069642 0.80 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Piperidine SCHEMBL21819962 0.80 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Piperidine SCHEMBL11283826 0.80
SCHEMBL11508384 0.80 ALDH1A1 (1.00) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6248849-B1 ADDITION POLYMER AMCOL CORPORATION 2001-06-19 US claimed
US-20200360242-A1 Oral Care Gel COLGATE-PALMOLIVE COMPANY (US) 2020-11-19 US disclosed
EP-3377025-A1 ORAL CARE GEL Colgate-Palmolive Company (US) 2018-09-26 EP disclosed
WO-2017095405-A1 ORAL CARE GEL COLGATE-PALMOLIVE COMPANY (US) 2017-06-08 WO disclosed
EP-1835968-B2 TOOTH WHITENING COMPOSITION CONTAINING CROSS-LINKED POLYMER-PEROXIDES COLGATE PALMOLIVE CO (US) 2015-04-01 EP disclosed
US-8568695-B2 Oral care composition with silicone composite COLGATE-PALMOLIVE COMPANY (US) 2013-10-29 US disclosed
EP-2012745-B1 ORAL CARE COMPOSITION WITH SILICONE COMPOSITE COLGATE PALMOLIVE CO (US) 2010-10-27 EP disclosed
EP-1835968-B1 TOOTH WHITENING COMPOSITION CONTAINING CROSS-LINKED POLYMER-PEROXIDES COLGATE PALMOLIVE CO (US) 2010-08-18 EP disclosed
EP-2012745-A1 ORAL CARE COMPOSITION WITH SILICONE COMPOSITE Colgate-Palmolive Company (US) 2009-01-14 EP disclosed
WO-2007130816-A1 ORAL CARE COMPOSITION WITH SILICONE COMPOSITE COLGATE-PALMOLIVE COMPANY (US) 2007-11-15 WO disclosed
US-5837790-A ALLYL METHACRYLATE COPOLYMER WITH ETHYLENE GLYCOL, DIMETHACRYLATE AS OIL ADSORBENT AMCOL INTERNATIONAL CORPORATION (US) 1998-11-17 US disclosed
US-5834577-A COMPRISING COPOLYMER OF ALLYL METHACRYLATE AND ETHYLENE GLYCOL DIMETHACRYLATE AMCOL INTERNATIONAL CORPORATION (US) 1998-11-10 US disclosed
US-5830960-A POLYMERIZING POLYUNSATURATED MONOMER IN SILICONE SOLVENT AMCOL INTERNATIONAL CORPORATION (US) 1998-11-03 US disclosed
US-5830967-A BUTYL METHACRYLATE-ALLYL METHACRYLATE-(OLIGO)ETHYLENE GLYCOL DIMETHACRYLATE TERPOLYMER AMCOL INTERNATIONAL CORPORATION (US) 1998-11-03 US disclosed
EP-0863160-A2 Process for producing an oil sorbent copolymer and the product thereof AMCOL INTERNATIONAL CORPORATION (US) 1998-09-09 EP disclosed
EP-0863159-A2 Precipitation polymerization process for producing an oil adsorbent polymer capable of entrapping solid particles and liquids and the product thereof AMCOL INTERNATIONAL CORPORATION (US) 1998-09-09 EP disclosed
US-5712358-A ALLYL METHACRYLATE AND AN ETHYLENE GLYCOL DIMETHACRYLATE, INTERFACIAL POLYMERIZATION, CROSSLINKING, POROSITY AMCOL INTERNATIONAL CORPORATION (US) 1998-01-27 US disclosed
EP-0417910-B1 Method of making highly adsorptive polymers BIOSYS INC (US) 1995-11-15 EP disclosed
EP-0417910-A2 Method of making highly adsorptive polymers Biosys, Inc. (US) 1991-03-20 EP disclosed
US-4962170-A PRECIPITATION POYMERIZING POLYUNSATURATED MONOMERS IN A MEDIUM THAT IS A SOLVENT FOR MONOMER AND A NONSOLVENT FOR POLYMER; DOW CORNING CORPORATION (US) 1990-10-09 US disclosed