Pyrrolidine

Pyrrolidine

SCHEMBL21327985

C1CCNC1.C=CC=C.[LiH]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
CXCR4 P61073 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HIF1A Q16665 1/20 0.33
MAPT P10636 1/20 0.33
PDE4A P27815 1/20 0.33
KDR P35968 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL2822529 0.93 ALDH1A1 (0.64) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Butadiene SCHEMBL15251839 0.84
Pyrrolidine SCHEMBL3748939 0.80
Pyrrolidine SCHEMBL8493241 0.79
Piperazine SCHEMBL1470254 0.77 HIF1A (0.50) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Pyrrolidine SCHEMBL27373182 0.76
Piperidine SCHEMBL2235377 0.76
SCHEMBL8467586 0.76
Azacyclotridecane SCHEMBL22607619 0.76 ALDH1A1 (0.90) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL28373479 0.76 ALDH1A1 (0.90) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3535302-B1 METHOD OF PRODUCING A MODIFIED DIENE-CONTAINING RUBBER, THE RUBBER AND A COMPOSITION BASED THEREON SIBUR HOLDING PUBLIC JOINT STOCK CO (RU) 2022-03-09 EP disclosed
CN-109906235-B Process for producing modified diene-containing rubbers, rubbers and compositions based thereon 公共型股份公司希布尔控股 2021-11-12 CN disclosed
US-11124590-B2 Method of producing a modified diene-containing rubber, the rubber and a composition based thereon Public Joint Stock Company “SIBUR Holding” (RU) 2021-09-21 US disclosed
US-20200262956-A1 METHOD OF PRODUCING A MODIFIED DIENE-CONTAINING RUBBER, THE RUBBER AND A COMPOSITION BASED THEREON PUBLIC JOINT STOCK COMPANY "SIBUR HOLDING" (RU) 2020-08-20 US disclosed
EP-3535302-A1 METHOD OF PRODUCING A MODIFIED DIENE-CONTAINING RUBBER, THE RUBBER AND A COMPOSITION BASED THEREON Public Joint Stock Company "Sibur Holding" (RU) 2019-09-11 EP disclosed
CN-109906235-A Produce method, rubber and the composition based on it of the modified rubber containing diene 公共型股份公司希布尔控股 2019-06-18 CN disclosed