Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28225634

C1CCOC1.Oc1ccccc1-n1nc2ccccc2n1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.50
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
LMNA P02545 1/20 0.49
KCNMA1 Q12791 1/20 0.39
HPGD P15428 3/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 2/20 0.36
HTT P42858 1/20 0.36
MGLL Q99685 1/20 0.36
MPO P05164 1/20 0.35
ALDH1A1 P00352 2/20 0.35
HSD17B10 Q99714 2/20 0.35
GLA P06280 1/20 0.35
IDO1 P14902 1/20 0.34
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CG P48736 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL59309 0.86 RAB9A (0.61) POLBNPC1RAB9ALMNAKCNMA1
SCHEMBL29363181 0.86 RAB9A (0.61) POLBNPC1RAB9ALMNAKCNMA1
Tetrahydrofuran SCHEMBL28244558 0.85 POLB (0.50) POLBNPC1RAB9ALMNAKCNMA1
Methane SCHEMBL10729260 0.84 RAB9A (0.59) POLBNPC1RAB9ALMNAKCNMA1
Alcohol SCHEMBL6573170 0.77 NPC1 (0.57) POLBNPC1RAB9ALMNAKCNMA1
SCHEMBL12415218 0.76 NPC1 (0.51) POLBNPC1RAB9ALMNAKCNMA1
Acetic Acid SCHEMBL2228922 0.76 NPC1 (0.56) POLBNPC1RAB9ALMNAKCNMA1
SCHEMBL28139129 0.74 POLB (0.62) POLBNPC1RAB9ALMNAKCNMA1
SCHEMBL29031120 0.73 RAB9A (0.51) POLBNPC1RAB9ALMNAKCNMA1
SCHEMBL31437603 0.73 RAB9A (0.51) POLBNPC1RAB9ALMNAKCNMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109313358-A Glasses lens 株式会社尼康依视路 2019-02-05 CN disclosed
CN-109313359-A Glasses lens 株式会社尼康依视路 2019-02-05 CN disclosed
CN-109071953-A Resin combination, cured film, the manufacturing method of cured film and display device 东丽株式会社 2018-12-21 CN disclosed
CN-105849155-B Composition for optical material and its manufacturing method 三菱瓦斯化学株式会社 2018-06-05 CN disclosed