Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | GPX4 | P36969 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26054452 | 0.81 | LMNA (0.48) | LMNAGLATYK2SMN1; SMN2HPGD | |
| SCHEMBL28838997 | 0.76 | LMNA (0.46) | LMNAGLATYK2SMN1; SMN2HPGD | |
| SCHEMBL16794591 | 0.74 | LMNA (0.54) | LMNAGLATYK2SMN1; SMN2HPGD | |
| SCHEMBL26544755 | 0.73 | LMNA (0.53) | LMNAGLATYK2SMN1; SMN2HPGD | |
| SCHEMBL18143596 | 0.73 | TYK2 (0.48) | LMNAGLATYK2SMN1; SMN2HPGD | |
| SCHEMBL5753871 | 0.72 | LMNA (0.36) | LMNAHPGDMAPK1KDM4EALDH1A1 | |
| SCHEMBL16198389 | 0.71 | LMNA (0.58) | LMNAGLASMN1; SMN2MAPK1KDM4E | |
| SCHEMBL12349896 | 0.71 | LMNA (0.58) | LMNAGLATYK2SMN1; SMN2HPGD | |
| SCHEMBL29686564 | 0.71 | TYK2 (0.56) | LMNAGLATYK2SMN1; SMN2HPGD | |
| SCHEMBL15181530 | 0.71 | LMNA (0.66) | LMNAGLAKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175408-B | Benzothiazole compound and its purposes as drug | 中国人民解放军第二军医大学 | 2018-07-17 | — | — | CN | disclosed |