Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28393099 | 0.82 | PTGS2 (0.40) | PTGS2LMNA | |
| SCHEMBL28227446 | 0.80 | USP7 (0.39) | PTGS2LMNA | |
| SCHEMBL30228339 | 0.77 | PTGS2 (0.38) | PTGS2LMNA | |
| SCHEMBL10768639 | 0.76 | LMNA (0.42) | LMNA | |
| SCHEMBL28226658 | 0.73 | PTGS2 (0.54) | PTGS2LMNA | |
| SCHEMBL28398241 | 0.72 | — | — | |
| SCHEMBL8140922 | 0.71 | PTGS2 (0.30) | PTGS2 | |
| SCHEMBL28398243 | 0.71 | — | — | |
| SCHEMBL2318517 | 0.71 | KDM4E (0.40) | — | |
| SCHEMBL19043946 | 0.71 | KDM4E (0.35) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108203450-B | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2020-05-19 | — | — | CN | disclosed |
| CN-108203450-A | Preparation method and application of amino phosphonate containing arylpyrazole compound | 南京工业大学 | 2018-06-26 | — | — | CN | disclosed |