Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 16/20 | 0.71 |
| ▸ | NPC1 | O15118 | 15/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | CASP3 | P42574 | 2/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334021 | 0.89 | RAB9A (0.87) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL28227108 | 0.84 | CASP3 (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL28466466 | 0.84 | RAB9A (0.74) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL3407604 | 0.83 | RAB9A (1.00) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL28226308 | 0.82 | LRRK2 (0.60) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL28226353 | 0.81 | DYRK1A (0.52) | RAB9ANPC1KDM4EPOLBMAPT | |
| SCHEMBL28466740 | 0.81 | RAB9A (0.72) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL28462117 | 0.81 | RAB9A (0.72) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL18562683 | 0.80 | RAB9A (0.71) | RAB9ANPC1ALDH1A1KDM4EPOLB | |
| SCHEMBL28226343 | 0.80 | DYRK1A (0.57) | RAB9ANPC1SMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105175408-B | Benzothiazole compound and its purposes as drug | 中国人民解放军第二军医大学 | 2018-07-17 | — | — | CN | disclosed |