SCHEMBL28228482

SCHEMBL28228482

N#Cc1c2ccccc2cc2cccc(-c3ccccc3)c12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SQOR Q9Y6N5 4/20 0.44
ADORA2A P29274 3/20 0.43
MAPK1 P28482 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ADORA1 P30542 2/20 0.43
CES1 P23141 1/20 0.41
ALDH1A1 P00352 6/20 0.41
HPGD P15428 5/20 0.41
KDM4E B2RXH2 4/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
MPI P34949 1/20 0.41
HSD17B10 Q99714 2/20 0.41
PIM1 P11309 2/20 0.40
CYP1A2 P05177 2/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20657064 0.84 CES1 (0.41) MAPK1L3MBTL1CES1ALDH1A1HPGD
SCHEMBL27721884 0.80 SQOR (0.53) SQORADORA2AMAPK1L3MBTL1ADORA1
SCHEMBL29663912 0.79 CES1 (0.42) MAPK1L3MBTL1CES1ALDH1A1HPGD
SCHEMBL28933823 0.79 CYP1A2 (0.41) L3MBTL1CES1ALDH1A1HPGDKDM4E
SCHEMBL186912 0.79 CES1 (0.42) MAPK1L3MBTL1CES1ALDH1A1HPGD
SCHEMBL819411 0.78 CA1 (0.49) MAPK1L3MBTL1CES1ALDH1A1HPGD
Anthracene SCHEMBL28247073 0.77 CES1 (0.41) MAPK1L3MBTL1CES1ALDH1A1HPGD
SCHEMBL2389040 0.77 CES1 (0.41) MAPK1L3MBTL1CES1ALDH1A1HPGD
SCHEMBL5745450 0.77 ALDH1A1 (0.44) ADORA2AADORA1CES1ALDH1A1HPGD
SCHEMBL29391266 0.76 ALDH1A1 (0.58) L3MBTL1ALDH1A1HPGDKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106146343-B A kind of compound and its synthetic method and application 上海和辉光电有限公司 2018-06-26 CN claimed
CN-109503427-B D-A type organic blue fluorescent material and preparation method and application thereof 陕西师范大学 2021-10-08 CN disclosed
CN-111362833-A Dianthracene D-delta-A type deep blue organic fluorescent material and preparation method and application thereof 陕西师范大学 2020-07-03 CN disclosed
CN-106146343-B A kind of compound and its synthetic method and application 上海和辉光电有限公司 2018-06-26 CN disclosed