Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18412850 | 0.87 | PIK3CA (0.39) | PIK3CAPIK3CDPIK3CBHSD17B10MAPK1 | |
| SCHEMBL20580048 | 0.84 | ALDH1A1 (0.47) | PIK3CAPIK3CDPIK3CBHSD17B10MAPK1 | |
| SCHEMBL18395143 | 0.84 | ALDH1A1 (0.47) | PIK3CAPIK3CDPIK3CBHSD17B10MAPK1 | |
| SCHEMBL20097527 | 0.82 | PIK3CA (0.37) | PIK3CAPIK3CDPIK3CBHSD17B10PIK3R1 | |
| SCHEMBL18412873 | 0.81 | ALDH1A1 (0.40) | PIK3CAPIK3CDPIK3CBPIK3R1ALDH1A1 | |
| SCHEMBL20580222 | 0.81 | ALDH1A1 (0.46) | PIK3CAHSD17B10MAPK1POLBALDH1A1 | |
| SCHEMBL24612210 | 0.80 | FBP1 (0.31) | KDM4EHTT | |
| SCHEMBL21755209 | 0.78 | PIK3CA (0.52) | PIK3CAPIK3CDPIK3CBHSD17B10MAPK1 | |
| SCHEMBL18395215 | 0.76 | ALDH1A1 (0.44) | PIK3CAHSD17B10MAPK1POLBALDH1A1 | |
| SCHEMBL18395121 | 0.76 | ALDH1A1 (0.43) | PIK3CAHSD17B10MAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108200760-A | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | 英安塔制药有限公司 | 2018-06-22 | — | — | CN | disclosed |