Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | RORB | Q92753 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6784901 | 0.80 | HTT (0.38) | RORARORCRORBPGRKDM4E | |
| SCHEMBL28228399 | 0.79 | MAPT (0.47) | MAPTHTTMAPK1NPSR1KMT2A | |
| SCHEMBL28289591 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1 | |
| SCHEMBL13304767 | 0.77 | RORA (0.55) | RORARORCRORBPGRKDM4E | |
| SCHEMBL19417174 | 0.77 | HRH1 (0.37) | RORARORCRORBPGRKDM4E | |
| SCHEMBL15854790 | 0.75 | RORA (0.47) | RORARORCRORBPGRKDM4E | |
| SCHEMBL5717794 | 0.74 | MIF (0.58) | POLBL3MBTL1MAPTHTTRAB9A | |
| SCHEMBL12374352 | 0.74 | RORA (0.69) | RORARORCRORBPGRKDM4E | |
| SCHEMBL16156848 | 0.74 | KDM4E (0.73) | RORARORCRORBPGRKDM4E | |
| SCHEMBL14261679 | 0.73 | RORA (0.46) | RORARORCRORBPGRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108329253-A | Preceding neurogenic compounds | 得克萨斯州大学系统董事会 | 2018-07-27 | — | — | CN | disclosed |