Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 5/20 | 0.34 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097322 | 0.82 | KDM4E (0.36) | L3MBTL1ALDH1A1KDM4EUSP2AR | |
| SCHEMBL28536056 | 0.74 | POLB (0.40) | POLBL3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL9899999 | 0.74 | AR (0.36) | ALDH1A1KDM4EUSP2ARMAPT | |
| SCHEMBL1899040 | 0.73 | ALDH1A1 (0.42) | L3MBTL1EGFRALDH1A1KDM4EMAPT | |
| SCHEMBL21708109 | 0.72 | L3MBTL1 (0.39) | POLBL3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL11358289 | 0.72 | POLB (0.39) | POLBL3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL28762463 | 0.71 | POLB (0.38) | POLBL3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL1965247 | 0.71 | POLB (0.38) | POLBL3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL27278791 | 0.71 | POLB (0.38) | POLBL3MBTL1HTR2AHTR2CALDH1A1 | |
| SCHEMBL1096638 | 0.70 | ALDH1A1 (0.44) | HTR2AALDH1A1KDM4EUSP2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105517993-B | Aryl amide kinase inhibitors | 百时美施贵宝公司 | 2018-07-13 | — | — | CN | disclosed |