Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL27279722 | 1.00 | NAAA (0.56) | NAAABCHEPPARGPPARDPPARA | |
| Decane SCHEMBL28276194 | 1.00 | NAAA (0.56) | NAAABCHEPPARGPPARDPPARA | |
| Decane SCHEMBL28087272 | 0.98 | NAAA (0.59) | NAAABCHEPPARGPPARDPPARA | |
| Hexane SCHEMBL27547172 | 0.95 | NAAA (0.56) | NAAABCHEEPHX1EPHX2 | |
| Hexadecane SCHEMBL28525033 | 0.91 | PLG (0.48) | NAAAPPARGPPARDPPARAHDAC11 | |
| Heptane SCHEMBL27728177 | 0.91 | PLG (0.48) | NAAAPPARGPPARDPPARAHDAC11 | |
| Octane SCHEMBL28203894 | 0.91 | PLG (0.48) | NAAAPPARGPPARDPPARAHDAC11 | |
| Heptadecanoic Acid SCHEMBL28221001 | 0.89 | GPR84 (0.61) | NAAAPPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL27304522 | 0.89 | GPR84 (0.61) | NAAAPPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL9077132 | 0.89 | GPR84 (0.61) | NAAAPPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349969-A | Substituted pyrazolo [1,5-a ] pyridine compounds as RET kinase inhibitors | 阵列生物制药公司 | 2018-07-31 | — | — | CN | disclosed |