Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27872024 | 0.82 | KDM4E (0.70) | KDM4EKMT2AMMP2ALOX15TSHR | |
| Benzene SCHEMBL27888317 | 0.80 | KDM4E (0.68) | KDM4EKMT2AMMP2ALOX15TSHR | |
| SCHEMBL1088781 | 0.80 | KDM4E (0.67) | KDM4EKMT2AMMP2ALOX15TSHR | |
| SCHEMBL30170409 | 0.79 | KDM4E (0.68) | KDM4EKMT2AMMP2ALOX15TSHR | |
| SCHEMBL7143621 | 0.79 | KDM4E (0.68) | KDM4EKMT2AMMP2ALOX15TSHR | |
| SCHEMBL29697210 | 0.79 | KDM4E (1.00) | KDM4EKMT2AMMP2ALOX15TSHR | |
| SCHEMBL171491 | 0.79 | KDM4E (1.00) | KDM4EKMT2AMMP2ALOX15TSHR | |
| Iodobenzene SCHEMBL28822053 | 0.78 | KDM4E (0.81) | KDM4EKMT2AMMP2ALOX15TSHR | |
| SCHEMBL3388245 | 0.78 | KDM4E (0.66) | KDM4EKMT2AMMP2ALOX15TSHR | |
| SCHEMBL4751890 | 0.78 | KDM4E (0.66) | KDM4EKMT2AMMP2ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | claimed |
| CN-108314647-A | A kind of preparation method of quinoline -2- formic acid and quinoline -2- formic acid derivates | 华中科技大学 | 2018-07-24 | — | — | CN | claimed |
| CN-108314647-B | Preparation method of quinoline-2-formic acid and quinoline-2-formic acid derivative | 华中科技大学 | 2020-06-26 | — | — | CN | disclosed |
| CN-108314647-A | A kind of preparation method of quinoline -2- formic acid and quinoline -2- formic acid derivates | 华中科技大学 | 2018-07-24 | — | — | CN | disclosed |