SCHEMBL30170409

SCHEMBL30170409

O=C(O)c1ccc2cccc(C(=O)O)c2n1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.68
KMT2A Q03164 2/20 0.68
MMP2 P08253 4/20 0.58
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.54
ACMSD Q8TDX5 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MGAM O43451 1/20 0.53
ALDH1A1 P00352 1/20 0.50
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
PIM1 P11309 1/20 0.47
NR4A1 P22736 1/20 0.47
NR4A2 P43354 1/20 0.47
NR4A3 Q92570 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7143621 1.00 KDM4E (0.68) KDM4EKMT2AMMP2ALOX15TSHR
SCHEMBL28798022 0.98 KDM4E (0.66) KDM4EKMT2AMMP2ALOX15TSHR
SCHEMBL27283354 0.98 KDM4E (0.66) KDM4EKMT2AMMP2ALOX15TSHR
SCHEMBL8490359 0.87 PIM1 (0.65) KDM4EKMT2AMMP2ALDH1A1LMNA
Benzene SCHEMBL27872024 0.83 KDM4E (0.70) KDM4EKMT2AMMP2ALOX15TSHR
Benzene SCHEMBL27888317 0.81 KDM4E (0.68) KDM4EKMT2AMMP2ALOX15TSHR
SCHEMBL1088781 0.81 KDM4E (0.67) KDM4EKMT2AMMP2ALOX15TSHR
SCHEMBL29697210 0.81 KDM4E (1.00) KDM4EKMT2AMMP2ALOX15TSHR
SCHEMBL171491 0.81 KDM4E (1.00) KDM4EKMT2AMMP2ALOX15TSHR
SCHEMBL1697008 0.81 ALDH1A1 (0.50) KDM4EKMT2AALOX15TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611932-B Preparation and application of dicarboxylic acid derivative capable of serving as GPR35 receptor fluorescent probe 中国科学院大连化学物理研究所 2025-01-14 CN claimed
US-20250213569-A1 METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY NEW YORK UNIVERSITY (US) 2025-07-03 US disclosed
CN-115611932-B Preparation and application of dicarboxylic acid derivative capable of serving as GPR35 receptor fluorescent probe 中国科学院大连化学物理研究所 2025-01-14 CN disclosed
CN-116897051-A Plasmin peptides for increasing therapeutic index 诺诺公司 2023-10-17 CN disclosed
CN-115551531-A Plasmin-cleavable PSD-95 inhibitor and reperfusion combined treatment of stroke 诺诺公司 2022-12-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250213569-A1 METHODS AND COMPOSITIONS FOR MEASURING AND INHIBITING EXONUCLEASE ACTIVITY DCLRE1B, RNASE1, ADAR KDM4E 4082/4885KMT2A 4125/4885MMP2 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.