Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720824 | 0.85 | KMT2A (0.42) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL29505627 | 0.85 | KMT2A (0.42) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL28231808 | 0.85 | MEN1 (0.41) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL28231761 | 0.85 | KMT2A (0.44) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL23632474 | 0.85 | MEN1 (0.44) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL28055302 | 0.84 | HTR3A (0.41) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL27546693 | 0.84 | KDM4E (0.56) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL11527133 | 0.83 | KDM4E (0.50) | KMT2AMEN1NPC1RAB9AGAA | |
| SCHEMBL29209989 | 0.83 | KMT2A (0.40) | KMT2AMEN1NPC1RAB9AGAA | |
| Hydrochloric Acid SCHEMBL28301754 | 0.82 | KDM4E (0.55) | KMT2AMEN1NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290878-A | NOVEL FERROPORTIN INHIBITORS | 威佛（国际）股份公司 | 2018-07-17 | — | — | CN | disclosed |