Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6231500 | 0.77 | ADRA2C (0.39) | ADRA2CMAPK1KMT2AMEN1PABPC1 | |
| SCHEMBL12753841 | 0.73 | MEN1 (0.36) | ADRA2CKMT2AMEN1 | |
| SCHEMBL4755963 | 0.67 | MEN1 (0.34) | ADRA2CMAPK1KMT2AMEN1 | |
| SCHEMBL21203108 | 0.67 | — | — | |
| SCHEMBL10746690 | 0.67 | ADRA2C (0.56) | ADRA2CMAPK1KMT2AMEN1PABPC1 | |
| SCHEMBL10746679 | 0.67 | ADRA2C (0.56) | ADRA2CMAPK1KMT2AMEN1PABPC1 | |
| SCHEMBL223179 | 0.67 | ADRA2C (0.56) | ADRA2CMAPK1KMT2AMEN1PABPC1 | |
| SCHEMBL1773641 | 0.67 | MEN1 (0.34) | ADRA2CMAPK1KMT2AMEN1 | |
| SCHEMBL1773222 | 0.67 | MEN1 (0.34) | ADRA2CMAPK1KMT2AMEN1 | |
| SCHEMBL19899357 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105229013-B | Epidithio dioxypiperazine piperazine compound or its derivative, and application thereof | 梨花女子大学校产学协力团 | 2018-09-14 | — | — | CN | disclosed |