Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28532387 | 0.84 | ELANE (0.42) | ALDH1A1ELANEGAAMEN1KMT2A | |
| SCHEMBL15526786 | 0.81 | ALDH1A1 (0.49) | ALDH1A1ELANEGAAMEN1KMT2A | |
| SCHEMBL1893211 | 0.77 | ALDH1A1 (0.51) | ALDH1A1ELANEGAAMEN1KMT2A | |
| SCHEMBL28232208 | 0.76 | DGAT1 (0.40) | GAAL3MBTL1 | |
| SCHEMBL28004709 | 0.76 | ELANE (0.54) | ALDH1A1ELANEGAAMEN1KMT2A | |
| SCHEMBL2159641 | 0.75 | ELANE (0.48) | ALDH1A1ELANEGAAMEN1KMT2A | |
| SCHEMBL2159275 | 0.74 | ALDH1A1 (0.49) | ALDH1A1ELANEGAAMEN1KMT2A | |
| SCHEMBL18709073 | 0.73 | DGAT1 (0.47) | GAAMEN1KMT2AMAPTKDM4E | |
| SCHEMBL11735907 | 0.72 | ALDH1A1 (0.44) | ALDH1A1ELANEGAAMEN1KMT2A | |
| SCHEMBL11735912 | 0.72 | ALDH1A1 (0.44) | ALDH1A1ELANEGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299532-B | Antiviral nucleoside analogue prodrug and composition and application thereof | 广东东阳光药业有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-108299532-A | A kind of antiviral nucleoside analogue prodrug and combinations thereof, purposes | 广东东阳光药业有限公司 | 2018-07-20 | — | — | CN | disclosed |