Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 2/20 | 0.36 |
| ▸ | SGK1 | O00141 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 5/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606933 | 0.67 | PDE2A (0.35) | SMN1; SMN2PKM | |
| SCHEMBL6604117 | 0.64 | PDE2A (0.34) | PKM | |
| SCHEMBL6605266 | 0.63 | KDM4E (0.36) | PKM | |
| SCHEMBL20837041 | 0.63 | KDM4E (0.53) | SGK1BRD4BRPF1PGAM1ACLY | |
| SCHEMBL8264979 | 0.62 | KMT2A (0.48) | SGK1BRD4BRPF1ACLYMAP2K4 | |
| SCHEMBL11052220 | 0.62 | EPHX1 (0.40) | SMN1; SMN2 | |
| SCHEMBL10650094 | 0.61 | BRD4 (0.52) | SGK1BRD4BRPF1PGAM1ACLY | |
| SCHEMBL10878124 | 0.61 | KDM4E (0.50) | SGK1BRD4PGAM1ACLY | |
| SCHEMBL29757952 | 0.61 | KMT2A (0.57) | LMNASMN1; SMN2BRD4PKM | |
| SCHEMBL10877471 | 0.60 | PDE4B (0.43) | SGK1BRD4PGAM1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440412-B | 2-pyrazole amide cyclohexyl sulfonamide compound, preparation method and application thereof | 沈阳农业大学 | 2021-04-13 | — | — | CN | claimed |
| CN-108440412-B | 2-pyrazole amide cyclohexyl sulfonamide compound, preparation method and application thereof | 沈阳农业大学 | 2021-04-13 | — | — | CN | disclosed |
| CN-108440412-A | A kind of 2- pyrazole amides cyclohexyl sulfonamide compounds, preparation method and applications | 沈阳农业大学 | 2018-08-24 | — | — | CN | disclosed |