Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 5/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 6/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837041 | 0.98 | KDM4E (0.53) | KDM4EGAAMAPTHDAC3HDAC1 | |
| SCHEMBL22290162 | 0.93 | PTGS1 (0.47) | KDM4EGAAMAPTHDAC3HDAC1 | |
| SCHEMBL29739977 | 0.93 | PTGS1 (0.47) | KDM4EGAAMAPTHDAC3HDAC1 | |
| SCHEMBL23014676 | 0.74 | ACLY (0.65) | KDM4EGAAMAPTPGAM1ACLY | |
| SCHEMBL23014672 | 0.74 | PGAM1 (0.49) | KDM4EPGAM1ACLYMRGPRX1PTGS1 | |
| SCHEMBL23014657 | 0.74 | PGAM1 (0.46) | KDM4EGAAPGAM1ACLYMRGPRX1 | |
| SCHEMBL13783840 | 0.74 | HDAC1 (0.53) | KDM4EGAAMAPTHDAC3HDAC1 | |
| SCHEMBL17404466 | 0.74 | BRD4 (0.51) | PGAM1ACLYPTGS1PTGS2BRD4 | |
| SCHEMBL449212 | 0.74 | KEAP1 (0.55) | KDM4EGAAMAPTPTGS1PTGS2 | |
| SCHEMBL29396266 | 0.74 | KEAP1 (0.55) | KDM4EGAAMAPTPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093591-B1 | SELECTIVE SULFONATION PROCESS | ELI LILLY AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |
| EP-0093591-A1 | Selective sulfonation process | ELI LILLY AND COMPANY (US) | 1983-11-09 | — | — | EP | disclosed |