⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958099 | 0.92 | — | — | |
| SCHEMBL8614311 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL6571777 | 0.89 | — | — | |
| SCHEMBL8613327 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL8617990 | 0.89 | TSHR (0.42) | — | |
| SCHEMBL8616144 | 0.89 | TSHR (0.42) | — | |
| Ethylamine SCHEMBL9461012 | 0.83 | DNM1 (0.42) | — | |
| SCHEMBL630936 | 0.81 | — | — | |
| Ethylamine SCHEMBL9620524 | 0.81 | DNM1 (0.41) | — | |
| Pyridine SCHEMBL9694965 | 0.76 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354557-A | Preparation method and application of 3-phenyl-2-propylene-1-one O-n-butyl oxime | 大连理工大学 | 2021-09-07 | — | — | CN | claimed |
| US-6933302-B2 | Nitrogen-based homo-camptothecin derivatives | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2005-08-23 | — | — | US | claimed |
| US-6855720-B2 | Nitrogen-based camptothecin derivatives | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2005-02-15 | — | — | US | claimed |
| US-20040063740-A1 | For treatment of cancer | SUTTER WEST BAY HOSPITALS, DBA CALIFORNIA PACIFIC MEDICAL CENTER | 2004-04-01 | — | — | US | claimed |
| US-20040034050-A1 | Homo-camptothecin derivatives | CATHOLIC HEALTHCARE WEST, DOING BUSINESS AS ST. MARY'S MEDICAL CENTER OF SAN FRANCISCO | 2004-02-19 | — | — | US | claimed |
| WO-2003101998-A1 | NITROGEN-BASED HOMO-CAMPTOTHECIN DERIVATIVES | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2003-12-11 | — | — | WO | claimed |
| WO-2003101406-A1 | HOMO-CAMPTOTHECIN DERIVATIVES | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2003-12-11 | — | — | WO | claimed |
| US-20030032624-A1 | Nitrogen-based camptothecin derivatives | US ARMY, SECRETARY OF THE ARMY | 2003-02-13 | — | — | US | claimed |
| WO-2022253283-A1 | PROTEIN KINASE DEGRADANT AND USE THEREOF | 中国科学院上海有机化学研究所 | 2022-12-08 | — | — | WO | disclosed |
| CN-113354557-B | Preparation method and application of 3-phenyl-2-propylene-1-one O-n-butyl oxime | 大连理工大学 | 2022-06-28 | — | — | CN | disclosed |
| CN-113354557-A | Preparation method and application of 3-phenyl-2-propylene-1-one O-n-butyl oxime | 大连理工大学 | 2021-09-07 | — | — | CN | disclosed |
| US-20170000132-A1 | BENZOXABOROLE FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20170000132-A1 | BENZOXABOROLE FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20150315146-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYLETHYNYL)-BICYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| US-5254717-A | Imino-substituted phenyl derivatives, the preparation thereof and fungicides containing these | BASF AKTIENGESELLSCHAFT (DE) | 1993-10-19 | — | — | US | disclosed |
| EP-0499823-A2 | Imino-substituted phenyl derivatives, their preparation and fungicides containing them | BASF Aktiengesellschaft (DE) | 1992-08-26 | — | — | EP | disclosed |
| EP-0463488-A1 | O-Benzyl oxime ethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-5037976-A | Antimicrobial Agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| US-4898859-A | 2-Oxa-isocephem compounds and compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-02-06 | — | — | US | disclosed |
| EP-0282895-A2 | 2-oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |