SCHEMBL28235161

SCHEMBL28235161

Cc1c(C)c(CCCCCCc2c(C)c(C)c(O)c(C)c2C)c(C)c(C)c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.38
ALOX5 P09917 8/20 0.35
PLA2G2A P14555 1/20 0.30
PLA2G5 P39877 1/20 0.30
ESR1 P03372 2/20 0.30
ADRA2A P08913 2/20 0.30
ADORA3 P0DMS8 2/20 0.30
TACR2 P21452 2/20 0.30
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 2/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
SHBG P04278 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
HSPD1 P10809 1/20 0.30
ADRB3 P13945 1/20 0.30
HTR2C P28335 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15234718 0.83 HPGD (0.46) TYRALOX5PLA2G2APLA2G5KDM4E
SCHEMBL7123817 0.80 ALOX5 (0.38) TYRALOX5KDM4EALDH1A1
SCHEMBL7607107 0.78 TYR (0.48) TYRALOX5PLA2G2APLA2G5ESR1
SCHEMBL14030867 0.78 TYR (0.48) TYRALOX5PLA2G2APLA2G5ESR1
SCHEMBL13427739 0.78 TYR (0.48) TYRALOX5PLA2G2APLA2G5ESR1
SCHEMBL12134619 0.78 TYR (0.48) TYRALOX5PLA2G2APLA2G5ESR1
SCHEMBL7328264 0.78 ALOX5 (0.36) TYRALOX5ALDH1A1LMNACYP3A4
SCHEMBL68926 0.75 FASN (0.35) ALOX5TP53HIF1A
SCHEMBL6268331 0.73 ALOX5 (0.36) ALOX5
Durohydroquinone SCHEMBL69786 0.73 ALOX5 (0.38) ALOX5ALDH1A1TP53CYP3A4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473671-A METHOD FOR PRODUCING POLYCARBONATE OLIGOMERS 国际壳牌研究有限公司 2018-08-31 CN disclosed
CN-108463481-A The method for preparing makrolon 国际壳牌研究有限公司 2018-08-28 CN disclosed
CN-108431080-A The method for preparing the oligomer for being used to prepare makrolon 国际壳牌研究有限公司 2018-08-21 CN disclosed