Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324230 | 0.91 | ALOX5 (0.38) | ALOX5 | |
| SCHEMBL12134619 | 0.82 | TYR (0.48) | ALOX5LMNAALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL13427739 | 0.82 | TYR (0.48) | ALOX5LMNAALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL7607107 | 0.82 | TYR (0.48) | ALOX5LMNAALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL14030867 | 0.82 | TYR (0.48) | ALOX5LMNAALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL7325280 | 0.78 | ALOX5 (0.41) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL7413599 | 0.78 | ALOX5 (0.41) | ALOX5LMNAPGRCYP3A4CYP2D6 | |
| SCHEMBL28235161 | 0.78 | TYR (0.38) | ALOX5LMNAALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL7330296 | 0.75 | TLR8 (0.35) | ALOX5LMNAALDH1A1HSD17B10PGR | |
| SCHEMBL7323576 | 0.75 | ALOX5 (0.38) | ALOX5LMNAPGRCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525361-A | FOR PHYSIOLOGICAL HOST DEFENSE CONTROL ACTIVITY IN MAMMALS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4407757-A | IMMUNOLOGY AGENT, MUSCLE RELAXANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-10-04 | — | — | US | disclosed |
| US-4271083-A | IMMUNO-POTENTIATING ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4139545-A | IMMUNO-POTENTIATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-02-13 | — | — | US | disclosed |