Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777912 | 0.89 | LOXL2 (0.64) | LOXL2MTNR1AMTNR1BHRH4KDM4E | |
| SCHEMBL1442945 | 0.89 | LOXL2 (0.64) | LOXL2MTNR1AMTNR1BHRH4KDM4E | |
| Hydrochloric Acid SCHEMBL6129294 | 0.87 | LOXL2 (0.62) | LOXL2MTNR1AMTNR1BHRH4KDM4E | |
| SCHEMBL7551798 | 0.79 | MTNR1A (0.55) | LOXL2MTNR1AMTNR1BHRH4MEN1 | |
| Tert-Butyl Formate SCHEMBL27999980 | 0.79 | LOXL2 (0.45) | LOXL2MTNR1AMTNR1BHRH4KDM4E | |
| SCHEMBL6253992 | 0.77 | MTNR1A (0.56) | LOXL2MTNR1AMTNR1BHRH4MEN1 | |
| SCHEMBL1327113 | 0.77 | LOXL2 (0.58) | LOXL2MTNR1AMTNR1BHRH4KDM4E | |
| SCHEMBL9027547 | 0.77 | LOXL2 (0.58) | LOXL2MTNR1AMTNR1BHRH4KDM4E | |
| SCHEMBL2261199 | 0.74 | LOXL2 (0.60) | LOXL2MTNR1AMTNR1BHRH4AHR | |
| SCHEMBL5642064 | 0.74 | LOXL2 (0.60) | LOXL2MTNR1AMTNR1BHRH4AHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732470-B | The high efficiency preparation method of 3- fluoro-indole-2-carbonyl compound | 暨南大学 | 2018-07-31 | — | — | CN | disclosed |