SCHEMBL28236157

SCHEMBL28236157

CC=CCc1cc(F)c(F)cc1F

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 8/20 0.44
FFAR1 O14842 4/20 0.30
FFAR4 Q5NUL3 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19186649 0.83 MAPT (0.34)
SCHEMBL900764 0.81 DPP4 (0.42) DPP4
SCHEMBL15853223 0.74 DPP4 (0.34) DPP4FFAR1FFAR4
SCHEMBL14920043 0.73 DPP4 (0.39) DPP4
SCHEMBL20860717 0.72 UHRF1 (0.34)
SCHEMBL2556351 0.71 DPP4 (0.38) DPP4
SCHEMBL1682063 0.71 GABRA1 (0.39) DPP4
SCHEMBL30096747 0.71 DPP4 (0.38) DPP4
SCHEMBL20631355 0.71 DPP4 (0.38) DPP4
SCHEMBL12954591 0.71 TAAR1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105315286-B The preparation of Xi Gelieting 连云港润众制药有限公司 2018-08-17 CN disclosed