Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2787229 | 0.92 | SMN1; SMN2 (0.51) | KDM4EHPGDLMNAMEN1KMT2A | |
| SCHEMBL793724 | 0.90 | MEN1 (0.65) | KDM4ESRD5A2HPGDLMNAMEN1 | |
| Hydrochloric Acid SCHEMBL514496 | 0.88 | MEN1 (0.63) | KDM4ESRD5A2HPGDLMNAMEN1 | |
| SCHEMBL14660694 | 0.88 | MEN1 (0.63) | KDM4ESRD5A2HPGDLMNAMEN1 | |
| SCHEMBL514495 | 0.87 | GLRA1 (0.65) | KDM4EHPGDLMNAMEN1KMT2A | |
| SCHEMBL18993390 | 0.87 | KDM4E (0.69) | KDM4EHPGDLMNAMEN1KMT2A | |
| SCHEMBL2343079 | 0.87 | MAOB (0.59) | KDM4EHPGDLMNASMN1; SMN2NPC1 | |
| Silver SCHEMBL14660693 | 0.87 | KDM4E (0.51) | KDM4EHPGDLMNAMEN1KMT2A | |
| SCHEMBL6659601 | 0.86 | ATM (0.61) | SRD5A2HPGDATMMEN1KMT2A | |
| SCHEMBL794412 | 0.85 | KMT2A (0.62) | KDM4EHPGDLMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440389-A | 3,4,5-trihydroxy benzoic acid derivative and the preparation method and application thereof | 山东大学 | 2018-08-24 | — | — | CN | disclosed |