Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16902987 | 0.90 | GLRA1 (0.61) | GLRA1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL10429197 | 0.89 | GLRA1 (0.64) | GLRA1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL11345190 | 0.89 | GLRA1 (0.60) | GLRA1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL28236202 | 0.87 | KDM4E (0.53) | KDM4EHPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL793724 | 0.87 | MEN1 (0.65) | KDM4EHPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL14660694 | 0.85 | MEN1 (0.63) | KDM4EHPGDLMNASMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL514496 | 0.85 | MEN1 (0.63) | KDM4EHPGDLMNASMN1; SMN2NPC1 | |
| SCHEMBL18993390 | 0.84 | KDM4E (0.69) | KDM4EHPGDLMNASMN1; SMN2NPC1 | |
| Silver SCHEMBL14660693 | 0.84 | KDM4E (0.51) | GLRA1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL1599431 | 0.84 | HPGD (0.59) | GLRA1KDM4EHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080070850-A1 | GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2008-03-20 | — | — | US | claimed |
| EP-1169304-B1 | 8-8, 6-6 AND 6-8 CATECHIN AND EPICATECHIN DIMERS AND METHODS FOR THEIR PREPARATION | MARS INC (US) | 2004-09-29 | — | — | EP | claimed |
| EP-1232169-A1 | GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-08-21 | — | — | EP | claimed |
| WO-2001036436-A1 | GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-05-25 | — | — | WO | claimed |
| US-6156912-A | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation | MARS, INCORPORATED (US) | 2000-12-05 | — | — | US | claimed |
| JP-4275296-A | — | — | None | — | — | JP | disclosed |
| US-12473264-B2 | Inhibitors of erythrocyte band 3 tyrosine phosphorylation and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2025-11-18 | — | — | US | disclosed |
| CN-114685574-B | Polyphenol compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2024-09-13 | — | — | CN | disclosed |
| CN-118598807-A | Application of polyphenol derivative prodrug compound in preparation of sucrose acetate isobutyrate long-acting slow-release in-situ gel | 沈阳药科大学 | 2024-09-06 | — | — | CN | disclosed |
| US-20220388968-A1 | INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2022-12-08 | — | — | US | disclosed |
| CN-114685574-A | Polyphenol compound and preparation method and application thereof | 中国科学院上海药物研究所 | 2022-07-01 | — | — | CN | disclosed |
| US-20210317068-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY | 2021-10-14 | — | — | US | disclosed |
| US-20040186167-A1 | Polyphenol proteasome inhibitors, synthesis, and methods of use | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2004-09-23 | — | — | US | disclosed |
| EP-1232169-A1 | GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036436-A1 | GALLOTANNINS AND ELLAGITANNINS AS REGULATORS OF CYTOKINE RELEASE | THE PENN STATE RESEARCH FOUNDATION (US) | 2001-05-25 | — | — | WO | disclosed |
| US-6156912-A | 88, 66, and 68 catechin and epicatechin dimers and methods for their preparation | MARS, INCORPORATED (US) | 2000-12-05 | — | — | US | disclosed |
| JP-H04275296-A | ADENOSINE DERIVATIVE AND ITS USE | GREEN CROSS CORP:THE | 1992-09-30 | — | — | JP | disclosed |
| US-4741915-A | PENTAGALLOYL GLUCOSE | NESTEC S.A. (CH) | 1988-05-03 | — | — | US | disclosed |
| US-4271193-A | PROPHYLAXIS AND TREATMENT OF GASTRITIS | KALI-CHEMIE PHARMA GMBH (DE) | 1981-06-02 | — | — | US | disclosed |
| EP-0006458-A1 | N1-Benzoyl-N2-phenyl-1,3-diaminopropane-2-ols and their salts, process for their preparation and medicaments containing them | Kali-Chemie Pharma GmbH (DE) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317068-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | GLRA1 1309/4885KDM4E 2744/4885HPGD 1458/4885 |
| US-20080070850-A1 | GALLOTANNINS AND ELLIGITANNINS AS REGULATORS OF CYTOKINE RELEASE | IL2, IL6, TNF | GLRA1 3243/4885KDM4E 2983/4885HPGD 536/4885 |
| US-20220388968-A1 | INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF | SPTBN1, CTTN, HBG1 | GLRA1 3222/4885KDM4E 2947/4885HPGD 4327/4885 |
| US-20040186167-A1 | Polyphenol proteasome inhibitors, synthesis, and methods of use | PSMC1, PSMB5, PSMC5 | GLRA1 4348/4885KDM4E 444/4885HPGD 1379/4885 |
| US-12473264-B2 | Inhibitors of erythrocyte band 3 tyrosine phosphorylation and uses thereof | HBG1, SPTBN1, CTTN | GLRA1 2105/4885KDM4E 2888/4885HPGD 4517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.