SCHEMBL28236259

SCHEMBL28236259

Cc1c(F)c(F)cc(CBr)c1F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28235044 0.82 DPP4 (0.31) DPP4
SCHEMBL826597 0.78 HDAC3 (0.33) DPP4
SCHEMBL719068 0.76 TAAR1 (0.41)
SCHEMBL169896 0.74 CA1 (0.38)
SCHEMBL4162574 0.74
SCHEMBL8894836 0.73
SCHEMBL2820568 0.73
SCHEMBL8895748 0.73
SCHEMBL5156289 0.73 P2RX7 (0.32)
SCHEMBL15312004 0.73 RIPK1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108368107-A FUSED HETEROCYCLIC COMPOUNDS AS S1P MODULATORS 艾伯维公司 2018-08-03 CN disclosed