Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11404384 | 0.87 | RAB9A (0.51) | SMN1; SMN2RAB9ANPC1HDAC6KDM4E | |
| SCHEMBL1160658 | 0.85 | MAPT (0.49) | SMN1; SMN2RAB9ANPC1HDAC6KDM4E | |
| SCHEMBL14369862 | 0.83 | NPC1 (0.55) | SMN1; SMN2RAB9ANPC1HDAC6KDM4E | |
| SCHEMBL25475197 | 0.81 | HDAC6 (0.47) | SMN1; SMN2RAB9ANPC1HDAC6KDM4E | |
| SCHEMBL25475152 | 0.79 | HDAC6 (0.48) | SMN1; SMN2RAB9ANPC1HDAC6HPGD | |
| SCHEMBL459471 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL30189629 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1KDM4EMAPT | |
| SCHEMBL2729927 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2RAB9ANPC1HDAC6KDM4E | |
| SCHEMBL4967068 | 0.73 | ATM (0.58) | SMN1; SMN2RAB9ANPC1HDAC6KDM4E | |
| SCHEMBL15987069 | 0.72 | ATM (0.53) | SMN1; SMN2RAB9ANPC1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409669-A | A kind of synthesis and application of the benzimidazolyl supermolecular gel factor based on Hofmann exhaustive methylation | 西北师范大学 | 2018-08-17 | — | — | CN | claimed |