Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.45 |
| ▸ | HSD11B2 | P80365 | 12/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823628 | 1.00 | HSD11B1 (0.45) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL2824811 | 0.88 | HSD11B1 (0.43) | HSD11B1HSD11B2 | |
| SCHEMBL2824814 | 0.88 | HSD11B1 (0.43) | HSD11B1HSD11B2 | |
| SCHEMBL2823380 | 0.83 | HSD11B1 (0.49) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL2823388 | 0.83 | HSD11B1 (0.49) | HSD11B1HSD11B2EPHX2 | |
| SCHEMBL2826086 | 0.83 | HSD11B1 (0.48) | HSD11B1HSD11B2 | |
| SCHEMBL2826088 | 0.83 | HSD11B1 (0.48) | HSD11B1HSD11B2 | |
| SCHEMBL2827326 | 0.82 | HSD11B1 (0.47) | HSD11B1HSD11B2 | |
| SCHEMBL2827328 | 0.82 | HSD11B1 (0.47) | HSD11B1HSD11B2 | |
| SCHEMBL2834255 | 0.81 | HSD11B1 (0.48) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | claimed |
| EP-2243479-A2 | Novel amide and amidine derivates and uses thereof | Abbott Laboratories (US) | 2010-10-27 | — | — | EP | disclosed |