Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10598999 | 0.97 | — | — | |
| SCHEMBL24491144 | 0.97 | — | — | |
| SCHEMBL6083299 | 0.97 | — | — | |
| SCHEMBL10599005 | 0.97 | — | — | |
| SCHEMBL15713527 | 0.90 | TSHR (0.50) | TSHRALDH1A1LMNACYP2C9HSD17B10 | |
| SCHEMBL23575220 | 0.90 | TSHR (0.50) | TSHRALDH1A1LMNACYP2C9HSD17B10 | |
| SCHEMBL9815760 | 0.87 | TSHR (0.47) | TSHRALDH1A1LMNACYP2C9HSD17B10 | |
| SCHEMBL23916930 | 0.87 | TSHR (0.47) | TSHRALDH1A1LMNACYP2C9HSD17B10 | |
| SCHEMBL4404822 | 0.87 | — | — | |
| SCHEMBL22417709 | 0.85 | TSHR (0.40) | TSHRALDH1A1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341830-A | Thienopyrimidine derivative and its application in drug | 广东东阳光药业有限公司 | 2018-07-31 | — | — | CN | disclosed |