⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059578 | 0.97 | ALDH1A1 (0.41) | — | |
| SCHEMBL13669624 | 0.97 | ALDH1A1 (0.41) | — | |
| SCHEMBL10598999 | 0.90 | — | — | |
| SCHEMBL10599005 | 0.90 | — | — | |
| SCHEMBL6083299 | 0.90 | — | — | |
| SCHEMBL24491144 | 0.90 | — | — | |
| SCHEMBL28236378 | 0.87 | TSHR (0.39) | — | |
| SCHEMBL15713527 | 0.83 | TSHR (0.50) | — | |
| SCHEMBL23575220 | 0.83 | TSHR (0.50) | — | |
| SCHEMBL2072181 | 0.82 | CYP2C9 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303599-A1 | PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. | 2023-09-28 | — | — | US | disclosed |
| EP-4192474-A1 | PRODRUGS OF PHOSPHONAMIDE NUCLEOTIDE ANALOGUES AND THEIR PHARMACEUTICAL USE | GILEAD SCIENCES, INC. (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-116194144-A | Prodrugs of phosphoramide nucleotide analogs and pharmaceutical uses thereof | 吉利德科学公司 | 2023-05-30 | — | — | CN | disclosed |
| EP-3192869-A1 | ISOLATED OLIGONUCLEOTIDE AND USE THEREOF IN NUCLEIC ACID SEQUENCING | BGI Shenzhen Co., Limited (CN) | 2017-07-19 | — | — | EP | disclosed |
| US-20120105185-A1 | METHOD FOR PRODUCING SINTERED FERRIT MAGNET, AND SINTERED FERRITE MAGNET | HITACHI METALS, LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-7198921-B2 | Process for producing protein with reduction of acidic sugar chain and glycoprotein produced thereby | MITSUBISHI PHARMA CORPORATION (JP) | 2007-04-03 | — | — | US | disclosed |