Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 13/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL297812 | 0.87 | EPHX1 (0.44) | EPHX1SMN1; SMN2ATMACHETSHR | |
| SCHEMBL28857974 | 0.78 | KDM4E (0.37) | EPHX1SMN1; SMN2ACHEALDH1A1HPGD | |
| SCHEMBL8951915 | 0.75 | EPHX1 (0.47) | EPHX1SMN1; SMN2ATMACHETSHR | |
| SCHEMBL28478171 | 0.71 | GAA (0.38) | CYP1A2CYP2C19SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL2829247 | 0.70 | EPHX1 (0.48) | EPHX1SMN1; SMN2ATMACHETSHR | |
| SCHEMBL1895878 | 0.69 | EPHX2 (0.44) | EPHX1ACHE | |
| Iodide SCHEMBL2310343 | 0.69 | EPHX1 (0.47) | EPHX1SMN1; SMN2ATMACHETSHR | |
| SCHEMBL5720644 | 0.68 | EPHX1 (0.40) | EPHX1ACHETSHRL3MBTL1NPC1 | |
| SCHEMBL81486 | 0.67 | ALDH1A1 (0.44) | EPHX1CYP1A2CYP2C19SMN1; SMN2ATM | |
| SCHEMBL7458589 | 0.66 | EPHX1 (0.52) | EPHX1SMN1; SMN2ATMACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |