Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 13/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1895878 | 0.86 | EPHX2 (0.44) | EPHX1ACHE | |
| SCHEMBL8951915 | 0.80 | EPHX1 (0.47) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL297812 | 0.78 | EPHX1 (0.44) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL2829247 | 0.75 | EPHX1 (0.48) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL9186839 | 0.75 | DGKA (0.55) | ALDH1A1TSHRNPSR1 | |
| Iodide SCHEMBL2310343 | 0.74 | EPHX1 (0.47) | EPHX1ACHEALDH1A1NPC1RAB9A | |
| SCHEMBL2138196 | 0.73 | DGKA (0.57) | ALDH1A1TSHRLMNANPSR1CA12 | |
| SCHEMBL4696577 | 0.72 | ACHE (0.62) | EPHX1ACHECA12CA14 | |
| SCHEMBL18197713 | 0.72 | PTPN7 (0.58) | ALDH1A1TSHRCA12CA14 | |
| SCHEMBL1696820 | 0.71 | ACHE (0.66) | EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599096-A4 | HETERO SUBSTITUED SODIUM CHANNEL BLOCKERS | PARION SCIENCES INC (US) | 2006-03-22 | — | — | EP | disclosed |
| EP-1599096-A2 | HETERO SUBSTITUED SODIUM CHANNEL BLOCKERS | Parion Sciences, Inc. (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004073629-A2 | HETERO SUBSTITUED SODIUM CHANNEL BLOCKERS | PARION SCIENCES, INC. (US) | 2004-09-02 | — | — | WO | disclosed |