Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 8/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSH | P09668 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828574 | 0.92 | SMN1; SMN2 (0.52) | TSHRSMN1; SMN2CTSKSIGMAR1KCNH2 | |
| SCHEMBL5599000 | 0.84 | ACE (0.46) | TSHRSMN1; SMN2CTSKCYP1A2CYP2C9 | |
| Benzene SCHEMBL28097533 | 0.84 | TSHR (0.86) | TSHRSMN1; SMN2CTSKCTSLCTSB | |
| SCHEMBL28689035 | 0.83 | CTSK (0.46) | TSHRSMN1; SMN2CTSKSIGMAR1CYP1A2 | |
| Toluene SCHEMBL28179722 | 0.83 | TSHR (0.66) | TSHRSMN1; SMN2CTSKCTSLCTSB | |
| Benzene SCHEMBL28179282 | 0.82 | TSHR (0.83) | TSHRSMN1; SMN2CTSKCTSLCTSB | |
| Phenol SCHEMBL27421781 | 0.82 | SMN1; SMN2 (0.63) | TSHRSMN1; SMN2CTSKCTSLCTSB | |
| Chlorobenzene SCHEMBL28128944 | 0.82 | SMN1; SMN2 (0.63) | TSHRSMN1; SMN2CTSKCTSLCTSB | |
| Fluorobenzene SCHEMBL27836900 | 0.82 | SMN1; SMN2 (0.63) | TSHRSMN1; SMN2CTSKCTSLCTSB | |
| SCHEMBL3366397 | 0.81 | TSHR (0.52) | TSHRSMN1; SMN2CTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-A | Compounds useful as TRPM8 modulators | 赛诺米克斯公司 | 2018-08-31 | — | — | CN | disclosed |