SCHEMBL1828574

SCHEMBL1828574

CCC(C=O)CCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.52
TSHR P16473 1/20 0.52
CTSK P43235 2/20 0.44
SIGMAR1 Q99720 2/20 0.43
KCNH2 Q12809 2/20 0.42
CHRM2 P08172 1/20 0.42
HTR1A P08908 1/20 0.42
ADRA2A P08913 1/20 0.42
CHRM1 P11229 1/20 0.42
DRD1 P21728 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
ADRA1A P35348 1/20 0.42
OPRM1 P35372 1/20 0.42
DRD3 P35462 1/20 0.42
SLC6A3 Q01959 1/20 0.42
EPHX2 P34913 2/20 0.41
KDM4A O75164 1/20 0.41
ACE P12821 1/20 0.41
GRIK1 P39086 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylbenzyl SCHEMBL28237241 0.92 TSHR (0.61) SMN1; SMN2TSHRCTSKSIGMAR1KCNH2
SCHEMBL5599000 0.89 ACE (0.46) SMN1; SMN2TSHRCTSKACE
SCHEMBL9819985 0.89 SIGMAR1 (0.48) SMN1; SMN2SIGMAR1KCNH2ADRA1ASLC6A3
SCHEMBL28689035 0.88 CTSK (0.46) SMN1; SMN2TSHRCTSKSIGMAR1KCNH2
SCHEMBL7279393 0.84 ACE (0.45) SMN1; SMN2SIGMAR1KCNH2ADRA1ASLC6A3
SCHEMBL27846682 0.78 SIGMAR1 (0.41) SIGMAR1KCNH2GRIK1
SCHEMBL585515 0.78 SIGMAR1 (0.45) SMN1; SMN2CTSKSIGMAR1KCNH2GRIK1
SCHEMBL28924030 0.78 SMN1; SMN2 (0.50) SMN1; SMN2ADRA1ASLC6A3EPHX2KDM4A
SCHEMBL11600192 0.78 L3MBTL1 (0.43) SMN1; SMN2TSHRCTSK
Toluene SCHEMBL28179722 0.77 TSHR (0.66) SMN1; SMN2TSHRCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2316025-A1 MEANS FOR THE DETECTION AND TREATMENT OF PROSTATE CELLS Eberhard-Karls-Universität Tübingen Universitätsklinikum (DE) 2011-05-04 EP claimed
WO-2010017986-A1 MEANS FOR THE DETECTION AND TREATMENT OF PROSTATE CELLS Eberhard-Karls-Universität Tübingen Universitätsklinikum (DE) 2010-02-18 WO claimed