Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 7/20 | 0.61 |
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27852060 | 0.92 | TSHR (0.60) | TSHRTP53HTTPLA2G4BRARB | |
| Terephthalic Acid SCHEMBL28336967 | 0.89 | TP53 (0.63) | TSHRTP53HTTPLA2G4BRARB | |
| Cetyl Palmitate SCHEMBL8430810 | 0.87 | TSHR (0.60) | TSHRTP53HTTPLA2G4BRARB | |
| Benzoic Acid SCHEMBL27584260 | 0.86 | TSHR (0.59) | TSHRTP53HTTPLA2G4BRARB | |
| SCHEMBL8775319 | 0.86 | RARB (0.59) | TSHRTP53PLA2G4BRARBDGKA | |
| SCHEMBL15286485 | 0.85 | TP53 (0.57) | TSHRTP53HTTPLA2G4BRARB | |
| Terephthalic Acid SCHEMBL17504571 | 0.84 | TP53 (0.65) | TSHRTP53HTTPLA2G4BRARB | |
| SCHEMBL12971158 | 0.83 | RAB9A (0.64) | TSHRDGKALMNAESR1CYP1A2 | |
| SCHEMBL43342 | 0.83 | DGKA (0.78) | TSHRDGKALMNATDP1 | |
| SCHEMBL28232643 | 0.83 | DGKA (0.78) | TSHRDGKALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115678160-B | Composition with laser marking function | 江苏臻远生物科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-115536943-B | Polypropylene plastic capable of being marked by laser | 江苏臻远生物科技有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-115678160-A | Composition with laser marking function | 江苏臻远生物科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-115536943-A | Polypropylene plastic capable of being marked by laser | 江苏臻远生物科技有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-113801400-A | Colorful laser etching composite material and preparation method thereof | 东莞市众一新材料科技有限公司 | 2021-12-17 | — | — | CN | claimed |
| CN-113736247-A | Polyamide composite material capable of being laser etched and preparation method thereof | 东莞市众一新材料科技有限公司 | 2021-12-03 | — | — | CN | claimed |
| CN-113072842-A | Preparation method of tourmaline modified solution capable of releasing negative ions | 深圳伟峰富氧健康管理实业有限公司 | 2021-07-06 | — | — | CN | claimed |
| CN-112080113-A | High-toughness flame-retardant PLA composite material and preparation method thereof | 方金丹 | 2020-12-15 | — | — | CN | claimed |
| CN-115678160-B | Composition with laser marking function | 江苏臻远生物科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-115536943-B | Polypropylene plastic capable of being marked by laser | 江苏臻远生物科技有限公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-115536943-A | Polypropylene plastic capable of being marked by laser | 江苏臻远生物科技有限公司 | 2022-12-30 | — | — | CN | disclosed |
| CN-113801400-A | Colorful laser etching composite material and preparation method thereof | 东莞市众一新材料科技有限公司 | 2021-12-17 | — | — | CN | disclosed |
| CN-113736247-A | Polyamide composite material capable of being laser etched and preparation method thereof | 东莞市众一新材料科技有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113736235-A | Biocompatible PLA composite material and preparation method thereof | 东莞市众一新材料科技有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113072842-A | Preparation method of tourmaline modified solution capable of releasing negative ions | 深圳伟峰富氧健康管理实业有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-112391035-A | Polyester film and method for producing same | 南亚塑胶工业股份有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-112080113-A | High-toughness flame-retardant PLA composite material and preparation method thereof | 方金丹 | 2020-12-15 | — | — | CN | disclosed |
| CN-106164170-B | Polyester mixture | 巴斯夫欧洲公司 | 2018-08-03 | — | — | CN | disclosed |