SCHEMBL28237487

SCHEMBL28237487

Cc1c(C(=O)C(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)cc1C(F)(F)F

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 17/20 0.76
PPARG P37231 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21632133 0.88 PTGDR2 (0.72) PTGDR2PPARG
SCHEMBL21695124 0.86 PTGDR2 (0.75) PTGDR2
Fevipiprant SCHEMBL1940595 0.86 PTGDR2 (1.00) PTGDR2
Fevipiprant SCHEMBL29355753 0.86 PTGDR2 (1.00) PTGDR2
SCHEMBL21632276 0.85 PTGDR2 (0.72) PTGDR2
SCHEMBL21695121 0.82 PTGDR2 (0.69) PTGDR2PPARG
SCHEMBL1940778 0.82 PTGDR2 (0.82) PTGDR2
SCHEMBL21591931 0.82 PTGDR2 (0.82) PTGDR2
SCHEMBL20508235 0.81 PTGDR2 (0.81) PTGDR2
SCHEMBL28356397 0.79 PTGDR2 (0.76) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108484595-A A kind of succinct synthetic method of asthmatic medicament Fevipiprant 天津科技大学 2018-09-04 CN claimed
CN-108484595-B Simple synthesis method of asthma medicine Fevipiprant 天津科技大学 2021-03-30 CN disclosed
CN-108484595-A A kind of succinct synthetic method of asthmatic medicament Fevipiprant 天津科技大学 2018-09-04 CN disclosed